REGION - NAME: Lazio Innova - KAY SYSTEMS ITALIA SRL

SECTOR: DIGITAL MEDICINE FOR CANCER THERAPY

TITLE: MRT-DSS: (MOLECULAR RADIO THERAPY-DECISION SUPPORT SYSTEM)

PROJECT DESCRIPTION:

Radiometabolic therapy consists in the administration of radioactive isotopes (radiopharma-ceuticals) and is widely used in the oncological field. Administration of radiopharmaceuticals labeled to the target tumor allows an effective and precision medicine that preserves healthy tissue while minimizing side effects and destroying cancer. This allows numerous advantages in terms of lengthening of the average life and improvement of the quality of life of patients with cancer. The attention of the medical world is increasingly focused on the development of new molecular radiopharmaceuticals for personalized medicine, which allow to be alternative or even to replace the traditional chemotherapy, such as in the metastatic prostate cancer or breast cancer using the 223Radium or with the new generation alpha-emitters like the 227Thorium to treat Non-Hodgkin's lymphomas. Because of the introduction of new advanced radiopharmaceuticals, patients' life expectancy has increased and with it radiometabolic therapy centers are expanding, in fact one million patients every year in Europe are treated with these nuclear methods. The project deals with the realization of a digital patient and avatar to personalized MR Treatment, a decision support system (DSS) for optimising and increasing MRT  effectiveness. A further innovative concept consists on the integration of the DSS with advanced wearable gamma cameras that strongly increase precision of treatment with a total comfort for patients.The results of the individual biokinetics study will be collected, and an integrative patient-specific digital representation achieved using radiological, functional and other nuclear medicine images, after improving the quality of the latter that is notoriously low. Population-specific data will be also used for treatment planning creating a patient avatar that consists of a multimodal representation as time changes (biokinetic, for all organs and tissues). Moreover, the DSS will support: establishing therapeutic effectiveness, absorbed dose-response and absorbed dose-toxicity correlations; combining several radiation therapy modalities for improving geometry; performing follow-up and future decisions for health care. These tasks will require a next-generation hardware design to guarantee computational efficiency, and new dedicated software, for dynamic managing of integrated 3D visualization of multi-modal images and dosimetry calculations.

BUSINESS OPPORTUNITY:

The goal of the project is to create a decision support system based on Digital patient. The multimodal management of morpho-functional images and the Treatment planning will be done by creating an AVATAR of the patient through an innovative SOFTWARE for Metabolic Radio Therapy/Radio Phamacy.

There are about 3.000 centers in EU and US that could be interested to buy and use this innovative System for a total market value of about 1,2B Euro.

CONTACT INFO:

Kay Systems Italia Srl

Website: www.ksi.it

e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Tel: +39.06.5427991

Contact person:

Mr. Matteo Viviano